How we build these pages

How Biomarker Bench researches, sources, and grades every page: primary-source evidence, A/B/C/D evidence grades, and separate all-things-considered tiers.

Evidence first, recall never

Every non-trivial claim is verified against a current primary source — a landmark randomized trial, a meta-analysis, or an authoritative guideline — and cited inline so you can check it yourself. We don’t publish numbers from memory, and we’re honest about null results: where treating or supplementing doesn’t help, we say so plainly.

Two ranks, not one

We separate evidence grade from recommendation. The evidence grade (A/B/C/D) reflects only how strong the proof is — an A requires replication on hard outcomes; Dmeans tested and null. The tier (S–D) is the all-things-considered call, factoring in cost, access, and effort. The same intervention can earn different tiers on different biomarker pages — and that’s correct.

Tailored, not templated

Each biomarker gets the page it needs. Some center on a ranked tier list of competing interventions; others, like vitamin D, center on a single lever and a dose calculator. We build the page around the reader’s real decision, not a fixed template.

Independent, and who stands behind it

Biomarker Bench sells nothing — no supplements, no tests, no sponsorships or affiliate links. Nothing on a page is placed because someone paid for it, so a tier or grade only ever reflects the evidence. Editorial work is led by Matt Palmieri, PhD(biotechnology) — a research scientist, not a physician. That’s the point of citing every claim: you don’t take our word for it, you follow the source. Every page carries a visible last-reviewed date.

Not medical advice

These are educational guides. Decisions about testing or treatment belong with your clinician.